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Purdue University Global
NU580 FNP II – Primary Care of Children and Adolescents’ Health
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This pediatric midterm study guide covers the most important assessment, diagnosis, management, and referral concepts for infants, children, and adolescents. High-yield topics include newborn respiratory conditions, dehydration, congenital heart disease, developmental milestones, adolescent health concerns, endocrine disorders, and preventive pediatric care. Understanding when to reassure, treat, monitor, or refer is essential for safe pediatric practice.
Transient tachypnea of the newborn occurs when fetal lung fluid is not completely cleared after birth. It is most common in full-term infants and typically resolves within 24 to 48 hours.
Clinical findings may include:
Rapid breathing shortly after birth
Mild respiratory distress
Nasal flaring or grunting
Oxygen requirement in some infants
Management is usually supportive, including monitoring oxygen levels and respiratory status.
Infant dehydration requires prompt assessment because young infants can deteriorate quickly.
Signs of dehydration include:
Decreased urine output
Dry mucous membranes
Sunken fontanelle
Poor feeding
Lethargy
Weight loss
Reduced tears
Management depends on severity:
Mild dehydration: Oral rehydration therapy with close monitoring
Moderate dehydration: Medical evaluation and possible supervised fluid replacement
Severe dehydration: Emergency care with intravenous fluids
Pyloric stenosis is caused by thickening of the pyloric muscle, leading to gastric outlet obstruction.
Typical findings include:
Projectile, non-bilious vomiting
Hunger after vomiting episodes
Weight loss or poor weight gain
Palpable “olive-shaped” abdominal mass
Treatment requires correction of dehydration and electrolyte abnormalities before surgical repair.
Hirschsprung disease results from the absence of ganglion cells in a portion of the colon, causing functional obstruction.
Symptoms include:
Delayed passage of meconium
Chronic constipation
Abdominal distention
Poor growth
Explosive stool after rectal examination
Diagnosis is confirmed through rectal biopsy. Surgical removal of the affected bowel segment may be required.
In utero hydronephrosis is detected through prenatal ultrasound and requires monitoring after birth.
Management may include:
Postnatal renal ultrasound
Monitoring urinary symptoms
Evaluation for urinary obstruction or reflux
Referral to pediatric urology when indicated
ASD commonly presents with:
Wide, fixed splitting of the second heart sound (S2)
Systolic flow murmur
VSD is characterized by:
Harsh holosystolic murmur
Murmur intensity depends on defect size
PDA findings include:
Continuous “machine-like” murmur
Bounding pulses
Possible widened pulse pressure
Findings may include:
Weak or delayed femoral pulses
Higher blood pressure in upper extremities
Lower blood pressure in legs
Systolic murmur
Pulmonic stenosis causes:
Harsh systolic crescendo-decrescendo murmur
Best heard at the left upper sternal border
Aortic stenosis presents with:
Loud harsh systolic crescendo-decrescendo murmur
Location at the upper right sternal border
Radiation to the neck
Common innocent murmurs include:
Still’s murmur: Musical or vibratory sound; louder when the child is supine
Pulmonary flow murmur
Venous hum
Characteristics requiring referral include:
Harsh quality
Diastolic murmurs
Symptoms such as poor feeding, cyanosis, or exercise intolerance
Infants should receive urgent cardiology evaluation when they have:
Oxygen saturation below 95%
Poor feeding
Cyanosis
Signs of heart failure
Abnormal cardiac examination findings
Children with congenital heart disease require cardiologist approval before participating in competitive sports.
Children with repaired congenital heart defects may require subacute bacterial endocarditis (SBE) prophylaxis with amoxicillin for six months after repair when indicated.
Children exposed to cardiopulmonary bypass, red blood cells, or plasma should avoid live vaccines for six months after surgery. Pneumococcal conjugate vaccine (PCV13) may still be administered because it is not a live vaccine.
Children with Down syndrome are at increased risk for complete atrioventricular canal defects.
Possible findings include:
Heart murmur
Poor feeding
Congestive heart failure symptoms
Poor weight gain
Normal pediatric blood pressure is based on age, sex, and height percentiles.
Classifications:
Normotensive: Below the 90th percentile
Elevated blood pressure: 90th to less than 95th percentile
Stage 1 hypertension: 95th percentile or 120/80 mmHg up to 5 mmHg above the 99th percentile
Stage 2 hypertension: Greater than the 99th percentile
Most pediatric hypertension is related to renal or renovascular causes.
Evaluation may include:
Urinalysis
Electrolytes
Renal function testing
Plasma renin testing
Children with persistent hypertension should be referred to specialists experienced in pediatric hypertension management.
Children with BMI above the 95th percentile require:
Nutrition counseling
Increased physical activity
Family-based lifestyle changes
Screening for obesity-related complications
Expected language milestones include:
Combining two words
Following simple commands
Expanding vocabulary rapidly
Speech delay requires developmental evaluation.
School-age children develop:
Friendships
Independence from parents
Academic skills
Social confidence
A child who avoids school, has poor grades, or frequently complains of illness may require evaluation for:
Learning disorders
Anxiety
Social difficulties
Evaluation of adolescent amenorrhea includes:
Pregnancy testing
Menstrual history
Assessment of nutrition and exercise patterns
Evaluation for endocrine disorders
Athletic adolescents may experience menstrual irregularities due to reduced body fat.
Possible findings include:
Testicular enlargement changes
Acne
Increased muscle mass
Mood changes
Altered puberty progression
Following stressful events, adolescents may show:
Withdrawal
Irritability
School difficulties
Changes in sleep or appetite
Counseling and mental health support may be recommended.
Infants treated for ROP require scheduled ophthalmology follow-up.
Any abnormal red reflex requires immediate referral.
Warning signs include:
Asymmetric reflexes
White reflex
Dark spots
Eye opacities
Retinoblastoma must be considered.
A four-month-old infant with suspected hearing loss requires:
Hearing screening
Audiologic evaluation
Developmental assessment
Signs may include:
Chronic diarrhea
Abdominal pain
Poor growth
Iron deficiency anemia
Infants with hypothyroidism require monitoring of:
Thyroid-stimulating hormone (TSH)
Free thyroxine (T4)
Primary care priorities include:
Blood glucose monitoring education
Insulin administration education
Recognition of hypoglycemia and diabetic ketoacidosis symptoms
Laboratory tests differentiating diabetes types include:
Autoantibodies
C-peptide levels
Possible findings include:
Developmental delay
Intellectual disability if untreated
Seizures
Musty body odor
Children suspected of metabolic disease require:
Immediate evaluation
Metabolic laboratory testing
Specialist referral
The American Academy of Pediatric Dentistry recommends the first dental visit:
When the first tooth erupts
No later than 12 months of age
Management may include:
Pain control
Observation in selected children
Amoxicillin as first-line antibiotic therapy when indicated
Ceftriaxone may be used when oral medications cannot be tolerated.
Children with recurrent abdominal pain and anemia require evaluation for organic causes.
Possible concerns include:
Gastrointestinal disease
Celiac disease
Inflammatory disorders
Referral is recommended when a child has:
Persistent academic difficulties
Poor grades despite intervention
Frequent school avoidance
Difficulty reading, writing, or mathematics
Behavioral concerns related to school performance
American Academy of Pediatrics. (2023). Bright Futures guidelines for health supervision of infants, children, and adolescents. American Academy of Pediatrics. https://brightfutures.aap.org
Centers for Disease Control and Prevention. (2024). Child and adolescent immunization schedule. CDC. https://www.cdc.gov/vaccines/schedules/
American Academy of Pediatric Dentistry. (2024). Guideline on infant oral health care. AAPD. https://www.aapd.org
Kliegman, R. M., St. Geme, J. W., Blum, N. J., Shah, S. S., & Tasker, R. C. (2023). Nelson textbook of pediatrics (22nd ed.). Elsevier. https://www.elsevier.com
Hagan, J. F., Shaw, J. S., & Duncan, P. M. (2017). Bright Futures: Guidelines for health supervision of infants, children, and adolescents (4th ed.). American Academy of Pediatrics.
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