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Purdue University Global
NU566 NP I – Introduction to Primary Care for the Nurse Practitioner
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A patient interview is the first and most important step in the clinical assessment process because it provides the subjective information needed to make accurate diagnoses and develop effective treatment plans. A well-structured interview helps healthcare providers identify health concerns, establish therapeutic relationships, improve patient safety, and guide evidence-based clinical decision-making. By following a systematic approach—from obtaining the chief complaint to completing the review of systems (ROS)—clinicians can gather comprehensive information while ensuring patients feel respected, understood, and actively involved in their care.
Whether you are a nurse practitioner, advanced practice registered nurse (APRN), or nursing student completing NU556 Unit 2, mastering patient interviewing skills is essential for delivering patient-centered healthcare.
Preparation begins before asking the first clinical question. Creating a comfortable, private, and distraction-free environment encourages patients to communicate openly and honestly. Professional introductions and identity verification also promote patient safety while establishing trust.
During the introduction, healthcare providers should:
Introduce themselves by name and professional role.
Ask how the patient prefers to be addressed.
Confirm the patient’s preferred pronouns.
Verify the patient’s full name and date of birth.
Explain their role during today’s visit.
Ensure privacy and maintain confidentiality.
Use open body language and maintain appropriate eye contact.
Building rapport early increases patient engagement and often results in more accurate and complete health information.
The Chief Complaint (CC) is the patient’s primary reason for seeking medical care. It is usually documented using the patient’s own words whenever possible and should remain concise.
Common chief complaints include:
Chest pain
Shortness of breath
Persistent cough
Headache
Abdominal pain
Fever
Back pain
Helpful opening questions include:
Why are you here today?
What brings you in today?
What concerns you the most?
How have you been feeling recently?
The chief complaint establishes the focus for the remainder of the clinical interview.
The History of Present Illness (HPI) provides a detailed description of the patient’s current health concern. It explores symptom development, progression, associated findings, and previous treatment attempts.
One of the most widely accepted methods for documenting the HPI is the OLD CARTS framework.
Determine when symptoms first appeared.
Questions may include:
When did your symptoms begin?
Did they start suddenly or gradually?
Are you still experiencing the symptoms?
Identify exactly where the symptom occurs.
Examples include:
Where do you feel the pain?
Does it radiate anywhere else?
Determine symptom frequency and length.
Ask questions such as:
How long does each episode last?
Are the symptoms constant or intermittent?
Have they become worse over time?
Ask patients to describe their symptoms in their own words.
Common descriptions include:
Sharp
Dull
Burning
Aching
Throbbing
Pressure
Stabbing
Identify activities or conditions that worsen symptoms.
Examples include:
Walking
Exercise
Eating
Movement
Stress
Position changes
Determine what improves symptoms.
Patients may report relief from:
Rest
Medication
Heat therapy
Ice
Position changes
Review previous interventions.
Ask about:
Prescription medications
Over-the-counter medications
Home remedies
Physical therapy
Previous medical evaluations
Also document:
Medication name
Dosage
Frequency
Effectiveness
Evaluate symptom intensity using standardized scales.
A commonly used question is:
“On a scale of 0 to 10, with 10 being the worst pain imaginable, how severe is your pain?”
Using OLD CARTS helps ensure no essential clinical details are overlooked while improving documentation consistency.
Medication reconciliation is a critical component of every patient interview because medication errors remain a leading cause of preventable adverse events.
Healthcare providers should document:
Prescription medications
Over-the-counter medications
Vitamins
Herbal products
Dietary supplements
Recently discontinued medications
Record:
Medication name
Dosage
Route
Frequency
Indication
Patient adherence
Example question:
“Can you tell me everything you currently take, including vitamins or herbal supplements?”
Allergy documentation helps prevent adverse drug reactions and improves patient safety.
Ask patients about:
Medication allergies
Food allergies
Environmental allergies
Latex allergy
Previous vaccine reactions
Always clarify the reaction experienced, such as:
Rash
Hives
Swelling
Difficulty breathing
Gastrointestinal symptoms
Anaphylaxis
Helpful questions include:
Are you allergic to any medications?
What happens when you’re exposed?
Have you ever experienced a severe allergic reaction?
Past medical history provides context that may influence diagnosis and treatment planning.
Review chronic illnesses including:
Hypertension
Diabetes mellitus
Asthma
Coronary artery disease
Chronic kidney disease
Cancer
Mental health disorders
Additional information should include:
Childhood illnesses
Pregnancy history
Previous diagnostic testing
Significant infectious diseases
Example questions:
Have you ever been diagnosed with any chronic medical conditions?
Have you experienced any serious illnesses in the past?
Previous surgeries and hospital admissions often affect current clinical management.
Document:
Surgical procedures
Approximate dates
Hospital admissions
Reasons for hospitalization
Surgical or postoperative complications
Example question:
“Have you ever had surgery or stayed overnight in a hospital?”
Family history identifies hereditary diseases and inherited risk factors.
Assess whether close relatives have experienced:
Heart disease
Hypertension
Diabetes
Stroke
Cancer
Mental illness
Thyroid disorders
Autoimmune diseases
Questions may include:
Are your parents living?
Do your siblings have any medical conditions?
Does your family have a history of cancer or heart disease?
A patient’s lifestyle often influences both disease risk and treatment outcomes.
Important areas include:
Education
Employment
Living situation
Relationship status
Diet and nutrition
Physical activity
Tobacco use
Alcohol consumption
Recreational drug use
Sexual history
Home safety
Exposure to violence
Example questions include:
What type of work do you do?
Do you currently smoke or vape?
How often do you drink alcohol?
Do you feel safe at home?
If tobacco use is identified, document:
Years smoked
Packs per day
Total pack-years
Previous quit attempts
Preventive care reduces disease burden through early detection and immunization.
Assess whether patients are current with recommended screenings, including:
Adult immunizations
Influenza vaccine
COVID-19 vaccination
Pap smear
Mammography
Colonoscopy
Prostate screening
Bone density testing
Testicular self-examination
Breast self-awareness
Questions may include:
Are your vaccinations up to date?
When was your last mammogram?
Have you ever had a colonoscopy?
The Review of Systems (ROS) is a systematic head-to-toe assessment used to identify symptoms affecting each major body system, including concerns unrelated to the chief complaint.
Assess:
Fever
Chills
Fatigue
Weight changes
Night sweats
Appetite changes
Review:
Rash
Bruising
Wounds
Color changes
Changes in moles
Assess:
Vision changes
Blurred vision
Eye pain
Corrective lens use
Review:
Hearing loss
Ear pain
Ringing in the ears
Ear drainage
Evaluate:
Nasal congestion
Nosebleeds
Difficulty swallowing
Sore throat
Hoarseness
Dental problems
Assess:
Breast pain
Lumps
Skin changes
Nipple discharge
Review:
Swollen lymph nodes
Easy bruising
Blood transfusions
Excessive thirst
Heat or cold intolerance
Appetite changes
Assess:
Chest pain
Palpitations
Edema
Orthopnea
Paroxysmal nocturnal dyspnea
Review:
Cough
Wheezing
Shortness of breath
Hemoptysis
History of tuberculosis
Pneumonia
Assess:
Abdominal pain
Nausea
Vomiting
Constipation
Diarrhea
Black or bloody stools
Hepatitis history
Review:
Dysuria
Frequency
Urgency
Sexual activity
Sexually transmitted infections
Contraceptive use
For female patients:
Last menstrual period
Pregnancy history
Pap smear
Mammogram
Vaginal discharge
For male patients:
Prostate symptoms
PSA testing
Urinary changes
Assess:
Joint pain
Joint swelling
Muscle weakness
Back pain
Osteoporosis
Fractures
Review:
Headaches
Dizziness
Weakness
Numbness
Seizures
Syncope
Paralysis
Assess:
Depression
Anxiety
Sleep disturbances
Mood disorders
Suicidal ideation
Previous psychiatric diagnoses
Once the health history is complete, clearly explain the next step before beginning the physical examination.
A professional transition statement might be:
“Thank you for answering my questions. Next, I’ll perform your physical examination to gather additional information about your health.”
Providing clear explanations helps reduce patient anxiety, improves cooperation, and supports a positive healthcare experience.
Healthcare professionals can improve interview quality by following several evidence-based communication strategies.
Key recommendations include:
Use open-ended questions before narrowing the discussion.
Practice active listening without interrupting the patient.
Maintain empathy and professional communication.
Avoid medical jargon whenever possible.
Summarize important information for accuracy.
Confirm patient understanding using teach-back techniques.
Document findings immediately and accurately.
Respect cultural differences and individual patient preferences.
A comprehensive patient interview serves as the cornerstone of accurate diagnosis and high-quality patient care. Following a structured process—including the chief complaint, history of present illness, medication review, allergy assessment, medical and surgical history, family history, social history, preventive health evaluation, and review of systems—helps clinicians collect complete and reliable health information.
Using standardized frameworks such as OLD CARTS, maintaining therapeutic communication, and documenting findings accurately improves clinical reasoning, patient safety, interdisciplinary collaboration, and evidence-based decision-making.
A patient interview gathers subjective health information, identifies the patient’s primary concerns, establishes therapeutic rapport, and provides the foundation for diagnosis, treatment planning, and clinical decision-making.
OLD CARTS stands for Onset, Location, Duration, Characteristics, Aggravating factors, Relieving factors, Treatments, and Severity. It is a structured framework used to assess the history of present illness.
The chief complaint identifies the patient’s primary reason for seeking healthcare and guides the direction of the clinical assessment, diagnostic testing, and treatment planning.
A complete medication history should include:
Prescription medications
Over-the-counter medications
Vitamins
Herbal supplements
Dietary supplements
Medication dosage
Route of administration
Frequency
Reason for use
The Review of Systems systematically evaluates every major body system, helping clinicians identify additional symptoms that may influence diagnosis, treatment decisions, or further diagnostic evaluation.
Healthcare providers should summarize the information collected, answer patient questions, explain the next steps, obtain consent before the physical examination, and ensure the patient understands the plan of care.
Agency for Healthcare Research and Quality. (2023). Communication and patient safety. https://www.ahrq.gov/patient-safety/index.html
Ball, J. W., Dains, J. E., Flynn, J. A., Solomon, B. S., & Stewart, R. W. (2023). Seidel’s guide to physical examination: An interprofessional approach (10th ed.). Elsevier. https://www.elsevier.com/books/seidels-guide-to-physical-examination/ball/978-0-323-76395-6
Bickley, L. S. (2024). Bates’ guide to physical examination and history taking (14th ed.). Wolters Kluwer. https://shop.lww.com/Bates%E2%80%99-Guide-to-Physical-Examination-and-History-Taking/p/9781975210878
Centers for Disease Control and Prevention. (2024). Adult immunization schedule by age group. https://www.cdc.gov/vaccines/hcp/imz-schedules/adult-age.html
Jarvis, C. (2024). Physical examination and health assessment (10th ed.). Elsevier. https://www.elsevier.com/books/physical-examination-and-health-assessment/jarvis/978-0-323-82462-6
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