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Western Governors University
D312 Anatomy and Physiology I with Lab
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Anatomy is the branch of biological science that focuses on studying the structure and organization of the human body. It involves examining the shape, size, and relationships between various body parts (Martini et al., 2021). For instance, studying the form and size of bones provides insight into how they support movement and protect organs. The intimate connection between structure and function underlies the foundation of anatomical science.
No two humans are structurally identical. These variations, referred to as anatomical anomalies, represent physical characteristics that differ from the standard pattern but may not necessarily indicate disease. Understanding these anomalies is essential for medical professionals to recognize what constitutes normal versus abnormal anatomy.
Anatomy can be divided into several specialized fields of study, each focusing on specific aspects of the human body.
| Type of Anatomy | Description | Example/Focus |
|---|---|---|
| Developmental Anatomy | Examines structural changes in the body from conception to adulthood. | Growth patterns during puberty. |
| Embryology | A branch of developmental anatomy that studies changes from conception to the end of the eighth week. | Early fetal development. |
| Cytology | Focuses on the microscopic features of cells. | Cell organelles and structures. |
| Histology | Studies tissues composed of cells and surrounding materials. | Epithelial or connective tissues. |
| Gross Anatomy | Observes structures visible without a microscope. | Studying bones, muscles, and organs. |
| Systemic Anatomy | Studies the body system by system. | Cardiovascular or respiratory system. |
| Regional Anatomy | Examines body areas as integrated units. | Head, chest, or abdomen. |
| Surface Anatomy | Observes external features to understand internal structures. | Palpating ribs or the sternum. |
| Anatomical Imaging | Uses technology such as X-rays, MRI, or ultrasound to visualize internal body structures. | MRI scans of the brain. |
Physiology is the scientific study of the functions and processes of living organisms. It seeks to explain how various body systems work together to maintain life and respond to environmental changes (Tortora & Derrickson, 2022). Physiology often studies systems rather than regions, aiming to predict body responses to stimuli and maintain internal stability.
| Field | Focus Area |
|---|---|
| Cell Physiology | Investigates processes occurring within cells. |
| Systemic Physiology | Examines functions of entire organ systems. |
| Neurophysiology | Studies functions of the nervous system. |
| Cardiovascular Physiology | Focuses on the heart and blood vessels. |
Together, anatomy and physiology form an inseparable pair: anatomy provides the structure, while physiology explains the function. Understanding both is essential to grasp how the human body maintains balance and performs complex biological tasks.
Pathology is the medical field that studies diseases and abnormal conditions, including their causes, development, and structural and functional impacts on the body. It bridges the gap between basic anatomy, physiology, and clinical medicine (Kumar et al., 2021).
The human body demonstrates six levels of structural organization, each progressively more complex than the last.
| Level | Description | Example |
|---|---|---|
| 1. Chemical Level | Atoms combine to form molecules essential for life. | Water, lipids, proteins. |
| 2. Cellular Level | Molecules form organelles within cells, the smallest living units. | Nucleus or mitochondria. |
| 3. Tissue Level | Groups of similar cells working together for a specific function. | Epithelial or muscle tissue. |
| 4. Organ Level | Two or more tissue types functioning together. | Heart, lungs, stomach. |
| 5. Organ System Level | Multiple organs functioning as a unit. | Digestive system. |
| 6. Organism Level | The complete living being, composed of organ systems working in harmony. | The human body. |
The human body contains 11 major organ systems, each performing distinct yet interdependent functions.
| System | Primary Function | Key Components |
|---|---|---|
| Integumentary | Protects the body, regulates temperature, and produces vitamin D. | Skin, hair, nails. |
| Skeletal | Provides support, protection, and movement; produces blood cells. | Bones, ligaments, joints. |
| Muscular | Facilitates movement, maintains posture, and generates heat. | Skeletal muscles, tendons. |
| Nervous | Detects sensations and controls movement and processes. | Brain, spinal cord, nerves. |
| Endocrine | Regulates metabolism, growth, and reproduction through hormones. | Pituitary, thyroid, adrenal glands. |
| Cardiovascular | Transports gases, nutrients, and wastes; regulates temperature. | Heart, blood, vessels. |
| Lymphatic | Defends against infection and maintains fluid balance. | Lymph nodes, vessels, spleen. |
| Respiratory | Facilitates gas exchange and regulates blood pH. | Lungs, trachea. |
| Digestive | Breaks down and absorbs nutrients; eliminates waste. | Stomach, intestines. |
| Urinary | Removes waste, regulates ion balance, and water content. | Kidneys, bladder. |
| Reproductive | Produces gametes and hormones for reproduction. | Testes, ovaries, uterus. |
All living organisms exhibit six fundamental characteristics that distinguish them from nonliving matter.
| Characteristic | Explanation |
|---|---|
| Organization | Refers to the precise arrangement of cells and structures within an organism. |
| Metabolism | Encompasses all chemical reactions, including energy production and synthesis. |
| Responsiveness | The ability to sense and respond to environmental changes. |
| Growth | Increase in cell size or number, leading to body enlargement. |
| Development | Involves growth, differentiation, and morphogenesis. |
| Reproduction | Formation of new cells or organisms, essential for species survival. |
Homeostasis is the body’s ability to maintain a stable internal environment despite external fluctuations. Each variable, such as temperature, is regulated around a set point within a normal range (Cannon, 1932).
| Mechanism | Description | Example |
|---|---|---|
| Negative Feedback | Restores conditions toward the set point when deviations occur. | Regulation of body temperature. |
| Positive Feedback | Enhances the deviation from the set point for specific purposes. | Childbirth contractions. |
Components of a Negative Feedback System:
Receptor – detects changes in a variable (e.g., thermoreceptors).
Control Center – determines the set point (e.g., hypothalamus).
Effector – acts to restore balance (e.g., sweat glands).
Failure in these mechanisms often leads to disease states such as diabetes or heart failure.
The anatomical position serves as the standard reference for describing body parts. It depicts a person standing upright, facing forward, arms at the sides, and palms facing outward.
| Position | Description |
|---|---|
| Supine | Lying face upward. |
| Prone | Lying face downward. |
| Term | Meaning | Example |
|---|---|---|
| Superior (Cephalic) | Toward the head | The chin is superior to the navel. |
| Inferior (Caudal) | Toward the tail | The navel is caudal to the chin. |
| Anterior (Ventral) | Toward the front | The sternum is anterior to the spine. |
| Posterior (Dorsal) | Toward the back | The spine is dorsal to the sternum. |
| Medial | Toward the midline | The nose is medial to the eyes. |
| Lateral | Away from the midline | The ears are lateral to the eyes. |
| Proximal | Closer to the trunk | The elbow is proximal to the wrist. |
| Distal | Farther from the trunk | The fingers are distal to the elbow. |
| Superficial | Toward the surface | Skin is superficial to muscles. |
| Deep | Away from the surface | Lungs are deep to the ribs. |
| Plane | Description |
|---|---|
| Sagittal Plane | Divides the body into right and left parts. |
| Median (Midsagittal) Plane | Divides the body into equal right and left halves. |
| Frontal (Coronal) Plane | Divides the body into anterior and posterior parts. |
| Transverse Plane | Divides the body into superior and inferior portions. |
| Oblique Plane | Cuts the body at an angle. |
The human body is divided into several major cavities that house vital organs.
| Cavity | Location | Major Organs |
|---|---|---|
| Cranial Cavity | Within the skull | Brain |
| Thoracic Cavity | Chest region | Heart, lungs |
| Abdominopelvic Cavity | Below the diaphragm | Stomach, liver, intestines, bladder |
Cannon, W. B. (1932). The Wisdom of the Body. W.W. Norton & Company.
Kumar, V., Abbas, A. K., & Aster, J. C. (2021). Robbins & Cotran Pathologic Basis of Disease (11th ed.). Elsevier.
Martini, F. H., Nath, J. L., & Bartholomew, E. F. (2021). Fundamentals of Anatomy & Physiology (12th ed.). Pearson.
Tortora, G. J., & Derrickson, B. (2022). Principles of Anatomy and Physiology (16th ed.). Wiley.
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